Table 1 Summary of demographics, behavior, and imaging measurements across within binge-prone cohort, obese binge-prone cohort, and lean binge-prone cohort.

From: Aberrant impulse control circuitry in obesity

 

Binge-prone cohort

 

All n = 37

Lean (BMI < 25) n = 19

Obese (BMI > 30) n = 13

Mann–Whitney U

pa

Age

26 ± 6

26 ± 6

27 ± 6

94

0.26

BMI

28 ± 8.5

21.8 ± 1.7

37.1 ± 7.6

–

–

Binge frequency (per week)

2.7 ± 1.4

2.5 ± 1.2

2.9 ± 1.7

108

0.56

Purging frequency (per week)

0.2 ± 0.5

0.03 ± 0.1

0.36 ± 0.7

155

0.16

BDI-I

13 ± 8.1

10.3 ± 8.0

17.2 ± 6.2

62

0.02

BAI

10.6 ± 7.2

11.2 ± 7.6

11.2 ± 7

119

0.88

DERS

96 ± 24

89 ± 25

102 ± 23

96

0.30

vmPFC-NAc shell rsFCb

0.11 ± 0.19

0.16 ± 0.15

0.05 ± 0.23

149

0.04

vmPFC-NAc shell R CI

0.87 ± 0.03

0.87 ± 0.03

0.85 ± 0.02

191

0.009

vmPFC-NAc shell L CI

0.84 ± 0.04

0.86 ± 0.05

0.82 ± 0.03

195

0.005

vmPFC thickness R

3.36 ± 0.45

3.48 ± 0.44

3.14 ± 0.4

183

0.02

vmPFC thickness L

3.37 ± 0.49

3.46 ± 0.46

3.2 ± 0.57

162

0.15

  1. Statistically significant p-values are in bold.
  2. BDI Beck’s depression inventory, BAI Beck’s anxiety inventory, DERS difficulties in emotion regulation scale.
  3. aMann–Whitney U test comparing lean and obese unless otherwise specified.
  4. bThree subjects were excluded from rsFC analysis due to imaging artifacts.
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