Fig. 1: MALDI-TOF images of mouse brains distribution of the Aβ1-6A2V peptide entirely composed of D-amino acids.
From: A novel bio-inspired strategy to prevent amyloidogenesis and synaptic damage in Alzheimer’s disease
Mice were sacrificed 4 (A), 24 (B) and 48 (C) hours after the last peptide administration. Control mice (D) were treated with saline solution. The lateral color bar indicates the peptide concentration in the different brain regions: blue, lower concentration; red, higher concentration. E shows a sagittal reference section from the Paxinos and Watson mouse brain atlas. The same peptide used for the mice treatment was used as a standard (F) for the correct peptide molecular weight identification in mouse brain areas.
