Table 1 Diagnostic criteria of a depressive episode in the DSM-5 and ICD-11.
Classification - syndrome definition | Diagnostic requirements | Severity assessment | Other | |
|---|---|---|---|---|
DSM-5 Single depressive episode (296.21 ff.) | Criteria: (1) depressed mood, (2) diminished interest or pleasure in activities, (3) significant weight or appetite change, (4) insomnia or hypersomnia, (5) psychomotor agitation or retardation, (6) low energy/fatigue, (7) feelings of worthlessness or inappropriate guilt, (8) reduced ability to concentrate or indecisiveness, (9) thoughts of death, suicidal ideation, and/or suicide attempts | Five or more symptoms for ≥ 2 weeks including (1) and/or (2) | Based on symptom amount and intensity and functional impairment (mild, moderate, severe). | 'Specifiers’ to represent clinical depression heterogeneity |
ICD-11 Single episode; depressive disorder (6A70 ff.) | Criteria: (1) depressed mood, (2) diminished interest or pleasure in activities, (3) low concentration, indecisiveness, (4) feelings of low self-worth, (5) hopelessness towards the future, (6) thoughts of death, suicidal ideation, and/or suicide attempts, (7) disturbed sleep pattern, (8) changes in appetite or weight, (9) psychomotor agitation or retardation, (10) low energy/fatigue | Significant distress or impairment in occupational, social, or other important areas of functioning. | Based on overall symptom intensity and functional impairment (mild, moderate, severe). | 'Qualifiers’ to represent clinical depression heterogeneity |
