Fig. 2: Bulk RNA-seq using iPSC-derived brain organoids from three male patients with OUD. | Molecular Psychiatry

Fig. 2: Bulk RNA-seq using iPSC-derived brain organoids from three male patients with OUD.

From: Single cell transcriptomics reveals distinct transcriptional responses to oxycodone and buprenorphine by iPSC-derived brain organoids from patients with opioid use disorder

Fig. 2

A Volcano plots indicate differentially expressed genes with FDR 0.05. B Pathway analysis of the bulk RNA-seq data was performed using gene set enrichment analysis (GSEA) software [43, 44]. NES is the normalized enrichment score to account for the size of each gene set.

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