Table 1 Participants with history of exposure to the assessed antidepressants.
From: Antidepressants that increase mitochondrial energetics may elevate risk of treatment-emergent mania
Mito+ antidepressants | N | TEM+ (n = 148) | TEM− (n = 452) |
Bupropion | 400 | 68 (17.0%) | 332 (83.0%) |
Nortriptyline | 29 | 2 (6.9%) | 27 (93.1%) |
Paroxetine | 227 | 49 (21.6%) | 178 (78.4%) |
Venlafaxine | 219 | 45 (20.6%) | 174 (78.4%) |
Mito− antidepressants | (n = 39) | (n = 250) | |
Amitriptyline | 61 | 5 (8.2%) | 56 (91.8%) |
Escitalopram | 250 | 35 (14.0%) | 215 (86.0%) |
