Table 1 Sample demographics.
From: Inflammation and cognition in severe mental illness: patterns of covariation and subgroups
SZ (N = 343) | BD (N = 289) | HC (N = 770) | p-value | Group comparisons | |
|---|---|---|---|---|---|
Age | 30.2 (10.2) | 32.8 (11.5) | 32.9 (9.1) | p < 0.001 | SZ < HC, BD |
Sex (m/f) | 188/155 | 114/175 | 423/347 | p < 0.001 | SZ, HC ~ BD |
Education (years) | 12.3 (2.3) | 13.6 (2.2) | 14.5 (2.2) | p < 0.001 | SZ < BD < HC |
WASI IQ (2-subtests) | 101 (13.6) | 109 (11.8) | 113 (10.4) | p < 0.001 | SZ < BD < HC |
BMI (kg/m2) | 26.3 (5.5) | 25.9 (4.6) | 24.7 (3.7) | p < 0.001 | SZ, BD > HC |
CRP | 3.3 (3.5) | 2.7 (3.0) | 2.2 (2.7) | p < 0.001 | SZ > HC, BD |
PANSS Negative | 13.4 (5.8) | 8.4 (3.4) | p < 0.001 | SZ > BD | |
PANSS Positive | 9.8 (4.2) | 5.8 (2.8) | p < 0.001 | SZ > BD | |
PANSS Disorganized | 5.6 (2.6) | 4.3 (1.6) | p < 0.001 | SZ > BD | |
PANSS Excited | 5.7 (2.1) | 5.2 (1.6) | p < 0.001 | SZ > BD | |
PANSS Depressed | 8.3 (3.3) | 7.7 (2.8) | ns | - | |
YMRS | 4.3 (4.8) | 3.4 (4.8) | ns | - | |
GAF Symptom | 45.1 (13.1) | 57.9 (11.2) | p < 0.001 | BD > SZ | |
GAF Function | 45.4 (13.0) | 55.8 (13.1) | p < 0.001 | BD > SZ | |
Age at onset | 23.8 (8.6) | 25.2 (9.5) | ns | - | |
Duration of illness (years) | 6.7 (8.0) | 7.4 (9.2) | ns | - | |
Antipsychotics, DDD | 1.0 (0.9) | 0.4 (0.7) | p < 0.001 | SZ > BD | |
Antidepressants, DDD | 0.4 (0.8) | 0.4 (0.8) | ns | - | |
Antiepileptics, DDD | 0.1 (0.2) | 0.3 (0.5) | p < 0.001 | BD > SZ | |
Lithium, DDD | 0.0 (0.1) | 0.2 (0.5) | p < 0.001 | BD > SZ | |
Total, DDD | 1.5 (1.4) | 1.3 (1.2) | ns | - |
