Table 1 Baseline sample characteristics from the Women’s Health Initiative Memory Study.
From: Plasma proteins related to inflammatory diet predict future cognitive impairment
Total Sample (n = 1528) | Low EDII (n = 764) | High EDII (n = 764) | ||
|---|---|---|---|---|
Demographics | EDIIa | −1.22 (1.97) | −2.85 (0.98) | 0.41 (1.24) |
DIIa | 1.25 (2.32) | 0.64 (2.37) | 1.86 (2.11) | |
Agea | 71.30 (3.75) | 71.67 (3.72) | 70.93 (3.74) | |
Female | 1528 (100.0%) | 764 (100.0%) | 764 (100.0%) | |
white | 1528 (100.0%) | 764 (100.0%) | 764 (100.0%) | |
Region | Northeast | 457 (29.9%) | 221 (28.9%) | 236 (30.9%) |
South | 329 (21.5%) | 181 (23.7%) | 148 (19.4%) | |
Midwesta | 356 (23.3%) | 152 (19.9%) | 204 (26.7%) | |
West | 386 (25.3%) | 210 (27.5%) | 176 (23.0%) | |
Treatment Assignment | Placebo | 744 (48.7%) | 377 (49.3%) | 367 (48.0%) |
Estrogen | 784 (51.3%) | 387 (50.7%) | 397 (52.0%) | |
Education | Less than high school | 78 (5.1%) | 32 (4.2%) | 46 (6.0%) |
High school or GEDa | 312 (20.5%) | 128 (16.8%) | 184 (24.2%) | |
Some college | 600 (39.4%) | 308 (40.4%) | 292 (38.4%) | |
Graduated collegea | 534 (35.0%) | 295 (38.7%) | 239 (31.4%) | |
APOEε4 Alleles | 0 ε4 alleles | 894 (58.5%) | 441 (57.7%) | 453 (59.3%) |
1-2 ε4 alleles | 634 (41.5%) | 323 (42.3%) | 311 (40.7%) | |
Cardiovascular Risk Factors | Hypertension | 729 (47.7%) | 353 (46.2%) | 376 (49.2%) |
Diabetes | 101 (6.6%) | 55 (7.2%) | 46 (6.0%) | |
Obesitya | 499 (32.8%) | 203 (26.6%) | 296 (39.1%) | |
Kidney Function | eGFR | 79.99 (12.82) | 80.05 (12.30) | 79.92 (13.33) |
Follow-Up Time | Years | 13.55 (5.20) | 13.40 (5.23) | 13.69 (5.17) |
Cognitive Status (At Final Follow-Up) | Cognitively Unimpaired | 716 (46.9%) | 359 (47.0%) | 357 (46.7%) |
Cognitively Impaired | 812 (53.1%) | 405 (53.0%) | 407 (53.3%) |
