Table 1 Comparison between patients with cocaine use disorder and healthy controls.

28

38

Gender

0.385^a

  Female

1 (3.57%)

4 (10.53%)

  Male

27 (96.43%)

34 (89.47%)

Age, years

  Mean (SD)

37.93 (7.89)

39.47 (11.49)

0.519^b

Having sons (N = 61)

0.110^c

  No

11 (42.31%)

22 (62.86%)

  Yes

15 (57.69%)

13 (37.14%)

Marital Status (N = 61)

0.604^a

  Single

13 (50.00%)

22 (62.86%)

  Married

12 (46.15%)

12 (34.29%)

  Divorced

1 (3.85%)

1 (2.86%)

Employment (N = 60)

1.000^c

  No

5 (20.00%)

7 (20.00%)

  Yes

20 (80.00%)

28 (80.00%)

Psychopharmaceuticals intake (N = 64)

<0.001^a

  No

17 (65.38%)

38 (100.00%)

  Yes

9 (34.62%)

0 (0.00%)

Previous psychiatric hospitalizations (N = 64)

0.013^a

  No

22 (84.62%)

38 (100.00%)

  Yes

4 (15.38%)

0 (0.00%)

Previous psychiatric diagnoses (N = 65)

<0.001^a

  No

16 (59.26%)

38 (100.00%)

  Yes

11 (40.74%)

0 (0.00%)

Smoking habit

0.513^c

  No

11 (39.29%)

18 (47.37%)

  Yes

17 (60.71%)

20 (52.63%)

BDNF levels (pg/ml)

<0.001^d

  Mean (SD)

18092.80 (6844.62)

11334.42 (5061.85)

ProBDNF levels (ng/ml)

<0.001^b

  Mean (SD)

87.03 (33.23)

55.70 (23.26)

ProBDNF/BDNF Ratio per mille

0.559^e

  Median (IQR)

4.74

5.04

  (4.40, 5.15)

(4.12, 6.69)