Table 2 Linear regression models predicting neurotrophin levels and proBNDF/BDNF ratio.

Cocaine consumption (yes)

4.26

0.39–8.46

0.033

23.59

3.69–43.49

0.023

2.35

−5.18 to 9.88

0.519

Age (years, continuous)

0.18

0.03–0.33

0.023

0.21

−0.53 to 0.95

0.557

−0.02

−0.28 to 0.24

0.864

Gender (female vs. male)

3.05

1.36–4.76

0.002

9.06

−4.02 to 22.14

0.162

−25.06

−48.24 to −1.88

0.036

Having sons (yes)

2.29

0.03–4.56

0.047

3.69

−15.66 to 23.05

0.692

−2.44

−9.61 to 4.74

0.483

 Married

−1.92

−5.26 to 1.41

0.242

−2.08

−27.65 to 23.49

0.866

2.90

−16.44 to 8.08

0.482

 Divorced

1.44

−5.30 to 2.41

0.441

0.08

−33.86 to 34.01

0.996

−4.18

−4.66 to 7.72

0.608

 Employment (yes)

−1.76

−6.15 to 2.64

0.411

1.50

−16.17 to 19.16

0.860

1.53

−3.08 to 8.88

0.320

 Psychopharmaceuticals intake (yes)

8.78

5.22–12.33

<0.001

42.71

19.95–65.46

0.001

7.64

−8.21 to 23.49

0.324

 Previous psychiatric hospitalizations (yes)

11.78

4.96–18.60

0.002

60.64

27.01–94.26

0.001

−0.70

−7.00 to 5.60

0.817

 Previous psychiatric diagnoses (yes)

−7.56

−13.43 to −1.68

0.015

−43.43

−66.76 to −20.10

0.001

−7.34

−22.06 to 7.39

0.308

 Smoking habit (yes)

−1.82

−4.67 to 1.03

0.195

−8.29

−25.21 to 8.70

0.318

2.77

−2.52 to 8.06

0.285

BDNF levels (μg/ml, continuous)

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−0.56

−1.82 to 0.71

0.366