Fig. 4: Gene PLS analysis and enrichment analyses.
From: Divergent suicidal symptomatic activations converge on somato-cognitive action network in depression
A Spatial map of PLS1 score in the left hemisphere. B The spatial correlation between the PLS1 score and the SA-related ANM in depression. C The ranked gene weights of PLS1 (PFDR < 0.001). D Left: The significantly enriched biological processes (PFDR < 0.05) of the PLS1+ gene set (q-value: the value from the Benjamini–Hochberg procedure for multiple comparison correction; color of the circle: different biological processes corresponding to the nodes of the enrichment network in the right). Right: Metascape enrichment network representing the similarities within each cluster and between clusters (circle nodes represent enriched biological processes; their size depends on the proportion of genes related to the enriched biological process among all input genes; nodes with the same color belong to the same cluster; nodes within the same cluster are typically similar to each other; biological processes with similarity >0.3 are connected through edges). E Left: The significantly enriched biological processes (PFDR < 0.05) of the PLS1− gene set. Right: Metascape enrichment network representing the similarities within each cluster and between clusters.
