Fig. 2: RNA sequencing revealed large-scale changes in gene expression in the dorsal striatum. | Molecular Psychiatry

Fig. 2: RNA sequencing revealed large-scale changes in gene expression in the dorsal striatum.

From: Incubation of methamphetamine craving in punishment-resistant individuals is associated with activation of specific gene networks in the rat dorsal striatum

Fig. 2

Analysis of raw sequencing data using Log2 fold changes and log10 p values revealed many differentially expressed genes in pairwise comparisons shown as volcano plots: (A) ASR vs CT, (B) DSR vs CT, (C) AS vs CT, (D) ASR vs AS, (E) DSR vs AS, (F) ASR vs DSR, (G) AS vs ASR and (H) AS vs DSR. I Hierarchical clustering of 1194 differentially expressed genes across six pair-wise comparisons. The red color represents over-expressed genes, the blue color represents genes with reduced expression, while the yellow color represents genes with no changes in expression. J Functional gene clusters and (K) KEGG analysis show pathway distribution of differentially expressed genes according to DAVID.

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