Table 1 Baseline demographic and clinical factors of randomized participants.

From: Comparative effectiveness research trial for antidepressant incomplete and non-responders with treatment resistant depression (ASCERTAIN-TRD) a randomized clinical trial

Variable

All N (%)

Aripiprazole augmentation N (%)

rTMS augmentation N (%)

Venlafaxine XR/Duloxetine Switch N (%)

Female

196 (70.5)

69 (74.1)

58 (69.0)

69 (68.3)

White

203 (74.3)

66 (72.5)

65 (80.2)

72 (71.2)

African

American

41 (15.0)

15 (16.4)

7 (8.6)

19 (18.8)

Race/Other

29 (10.6)

10 (10.9)

9 (11.1)

10 (9.9)

Hispanic ethnicity

29 (10.5)

9 (9.6)

6 (7.1)

14 (14.2)

Variable

All mean (SD)

Aripiprazole augmentation mean (SD)

TMS augmentation mean (SD)

Venlafaxine XR/Duloxetine switch mean (SD)

Age (years)

45.6 (15.3)

47.0 (16.1)

43.8 (14.5)

45.6 (15.3)

Number of failed trials

2.85 (1.0)

Median = 3

25th

percentile = 2

75th

percentile = 3

Minimum = 2

Maximum = 8

2.94 (1.1)

Median = 3

25th

percentile = 2

75th

percentile = 3

Minimum = 2

Maximum = 8

2.82 (1.0)

Median = 2.5

25th

percentile = 2

75th

percentile = 3

Minimum = 2

Maximum = 6

2.80 (0.9)

Median = 3

25th

percentile = 2

75th

percentile = 3

Minimum = 2

Maximum = 6

MADRS total score

32.6 (6.3)

Median = 32

25th

percentile = 28

75th

percentile = 37

Minimum = 20

Maximum = 46

33.1 (6.0)

Median = 33

25th percentile = 29

75th percentile = 37

Minimum = 20

Maximum = 46

33.1 (6.0)

Median = 33

25th percentile = 29

75th percentile = 38

Minimum = 21

Maximum = 45

33.0 (6.0)

Median = 32

25th percentile = 28

75th percentile = 38

Minimum = 21

Maximum = 46

SDQ total score

156.1 (25.4)

Median = 154

25th

percentile = 138

75th

percentile = 174

155.2 (22.8)

Median = 155

25th

percentile = 138

75th

percentile = 169

155.9 (26.1)

Median = 155

25th

percentile = 138

75th

percentile = 175

156.9 (27.1)

Median = 153

25th

percentile = 140

75th

percentile = 177

 

Minimum = 95

Maximum = 223

Minimum = 113

Maximum = 205

Minimum = 95

Maximum = 222

Minimum = 96

Maximum = 223

  1. MADRS Montgomery Asberg Depression Rating Scale, rTMS Repetitive Transcranial Magnetic Stimulation, SD standard deviation, SDQ Symptoms of Depression Questionnaire.