Fig. 1: Network of white matter fiber tracts that are positively associated with processing speed across diagnostic groups. | Molecular Psychiatry

Fig. 1: Network of white matter fiber tracts that are positively associated with processing speed across diagnostic groups.

From: The interplay between polygenic score for tumor necrosis factor-α, brain structural connectivity, and processing speed in major depression

Fig. 1

A Dorsal, lateral, and medial views of the network of white matter fiber tracts in which connectivity strength, measured with edge-wise fractional anisotropy (FA), was positively associated with processing speed (z-score) across diagnostic groups. The network was identified using the Network-based statistic (NBS) toolbox (NBS t-threshold = 2.0, pFWE < 0.001), while correcting for age, sex, and scanner site. See Supplement 13 for details on participating anatomical brain regions. Network plots were created using BrainNet Viewer. B Scatterplot depicting the positive association between mean FA and processing speed across patients with acute (MDDa), partially (MDDpr), and fully remitted (MDDfr) major depressive disorder and healthy controls (HC). A more positive processing speed score represents higher processing speed performance.

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