Fig. 3: Group differences in differential blood oxygen level dependent (BOLD) responses induced by conditioned interoceptive pain predictors (i.e., ΔCSVISC) in the extinction phase in patients with ulcerative colitis (UC) compared to patients with irritable bowel syndrome (IBS). | Molecular Psychiatry

Fig. 3: Group differences in differential blood oxygen level dependent (BOLD) responses induced by conditioned interoceptive pain predictors (i.e., ΔCSVISC) in the extinction phase in patients with ulcerative colitis (UC) compared to patients with irritable bowel syndrome (IBS).

From: Disease-specific alterations in central fear network engagement during acquisition and extinction of conditioned interoceptive fear in inflammatory bowel disease

Fig. 3

For visualization purposes, activations were superimposed on a structural T1-weighted MR-image, thresholded at p < 0.01 uncorrected, and masked for the a-priori defined regions of interest. The color bar indicates t-scores (for statistical details, see Table 2), and parameter estimates are provided to indicate the direction of effects. aINS anterior insula, a.u. arbitrary units, CS conditioned stimulus.

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