Fig. 5: CeA-projecting PSTNTac1 neurons delay refeeding while CeA-projecting PSTNCrh neurons hasten refeeding. | Molecular Psychiatry

Fig. 5: CeA-projecting PSTNTac1 neurons delay refeeding while CeA-projecting PSTNCrh neurons hasten refeeding.

From: The parasubthalamic nucleus refeeding ensemble delays feeding initiation and hastens water drinking

Fig. 5

A Experimental design and representative images of mCherry fluorescence illustrating hM3Dq expression in CeA-projecting PSTNTac1 (B, C) and PSTNCrh (D, E) neurons (scale bars: gray, 500 μm; white, 200 μm). Behavioral testing was performed 30 min after injection of CNO or vehicle, and 24 h after food deprivation (B, D) or 4 h after water deprivation (C, E). In each panel, the latency to initiate feeding/drinking is shown on the left and the amount of food/fluid consumed is shown on the right. Bars represent mean ± s.e.m. and individual values are overlaid. Data were analyzed using paired t tests, *p < 0.05; ***p < 0.001.

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