Table 1 Study sample characteristics by sex: UK biobank 2006–2021.

From: Mediating and moderating effects of plasma proteomic biomarkers on the association between poor oral health problems and brain white matter microstructural integrity: the UK Biobank study

 

Overall (N = 5089)

Men (N = 2368)

Women (N = 2721)

Psex

Demographic, means ± SE or %

 Baseline age, y

54.57 ± 0.11

55.3 ± 0.16

53.9 ± 0.14

<0.001

 Sex, % female

53.4%

0.0

100.0

 

 Race/ethnicity

 White

96.8%

96.7%

96.9%

(Ref)

 Black

0.8%

0.9%

0.7%

0.45

 South Asian

0.8%

1.0%

0.6%

0.12

 Other

1.6%

1.4%

1.8%

0.37

 Non-White, %

3.2

3.3

3.1

0.62

 Household size

2.605 ± 0.016

2.670 ± 0.024

2.549 ± 0.023

<0.001

Socioeconomic, means ± SE or %

 Education

  Low

15.3%

16.3%

14.5%

0.89

  Intermediate

34.8%

31.0%

38.1%

<0.001

  High

49.9%

52.7%

47.4%

(Ref)

 Income

  Less than £18,000

11.1%

8.6%

13.3%

<0.001

  £18,000–£29,999

22.0%

20.4%

23.4%

0.039

  £30,000–£51,999

30.0%

30.5%

29.6%

(Ref)

  £52,000–£100,000

29.0%

31.4%

26.7%

0.079

  greater than £100,000

8.0%

9.1%

7.0%

0.043

  Townsend Deprivation Index

−1.754 ± 0.040

−1.794 ± 0.058

−1.718 ± 0.054

0.34

SES

−0.010 ± 0.009

+0.033 ± 0.014

−0.047 ± 0.013

<0.001

Poor oral health problems, POHP, %

10.9

12.3

9.6

0.002

Life’s essential 8, means ± SE

 Total score

533.1 ± 1.3

515.8 ± 1.8

548.1 ± 1.8

<0.001

 Lifestyle score

262.3 ± 0.8

257.5 ± 1.2

266.5 ± 1.1

<0.001

 Biological score

271.3 ± 0.9

258.5 ± 1.3

282.4 ± 1.3

<0.001

Brain dMRI metrics, means ± SE

Mean FA

+0.5616 ± 0.0003

+0.5617 ± 0.0004

+0.5616 ± 0.0004

0.90

Mean MD

+0.00079 ± 4.67e-07

+0.00080 ± 6.97e-07

+0.00080 ± 6.29e-07

<0.001

Mean ICVF

+0.6121 ± 0.0005

+0.6117 ± 0.0006

+0.6124 ± 0.0005

0.39

Mean ISOVF

+0.0940 ± 0.0002

+0.0952 ± 0.0003

+0.0930 ± 0.0003

<0.001

Mean OD

+0.1276 ± 0.0001

+0.1277 ± 0.0002

+0.1275 ± 0.0002

0.56

  1. No multiple imputation was carried out in this analysis. P-value is associated with the parameter for sex in bivariate linear and multinomial logistic regression analyses, with the main outcome being a continuous or categorical characteristic, respectively. (Ref) is the referent category in the multinomial logistic regression model. Values are means ± SE or percentages.
  2. FA Fractional Anisotropy, ICVF Intracellular Volume Fraction, ISOVF Isotropic Volume Fraction, LE8 Life’s Essential 8, MD Mean Diffusivity, OD Orientation Dispersion, Pd Periodontal Disease, POHP Poor Oral Health Problems, SES Socio-economic Status, UK United Kingdom.
Back to article page