Table 1 Clinical and sociodemographic characteristics.
MDD serum hsCRP < 1 mg/L n = 39 | MDD serum hsCRP 1–3 mg/L n = 31 | MDD serum hsCRP > 3 mg/L n = 35 | Controls n = 34 | Group tests (Statistics and p values) and post-hoc analyses | |
|---|---|---|---|---|---|
Serum hsCRP (mg/L) mean (± SD) | n = 39 | n = 31 | n = 35 | n = 34 | H = 101.40, p < 0.001 MDD CRP > 3 vs. others MDD CRP 1–3 vs. controls and vs. MDD CRP < 1 |
0.55 ( ± 0.25) | 1.56 ( ± 0.55) | 5.37 ( ± 2.50) | 1.04 ( ± 0.88) | ||
Age (years) mean (± SD) | n = 39 | n = 31 | n = 35 | n = 34 | F = 0.397, p = 0.756 |
34.79 ( ± 7.44) | 35.94 ( ± 7.68) | 36.71 ( ± 7.48) | 35.85 ( ± 7.96) | ||
Sex n (%) | n = 39 | n = 31 | n = 35 | n = 34 | χ2 = 3.072*, p = 0.381 |
Females: 23 (58.97%) | Females: 22 (70.97%) | Females: 27 (77.14%) | Females: 22 (64.71%) | ||
Ethnicity n (%) | n = 39 | n = 29 | n = 35 | n = 34 | χ2 = 12.772*, p = 0.005 |
White: 36 (92.31%) | White: 25 (86.21%) | White: 30 (85.71%) | White: 21 (61.76%) | ||
BMI (Kg/m2) mean (± SD) | n = 39 | n = 30 | n = 34 | n = 33 | F = 16.527, p < 0.001 |
24.57 ( ± 2.58) | 27.56 ( ± 4.83) | 30.12 ( ± 4.11) | 24.52 ( ± 4.03) | MDD CRP > 3 vs. controls and vs. MDD CRP < 1 MDD CRP 1–3 vs. controls and MDD CRP < 1 | |
Exposure and response to antidepressant treatment n (%) | n = 39 MDD treatment responsive: 15 (38.46%) MDD treatment non-responsive: 17 (43.59%) MDD unmedicated: 7 (17.95%) | n = 31 MDD treatment responsive: 12 (38.71%) MDD treatment non-responsive: 10 (32.26%) | n = 35 MDD treatment responsive: 9 (25.71%) MDD treatment non-responsive: 20 (57.14%) | n = 34 | χ2 = 4.75*, p = 0.309 Across the MDD subgroups only (no controls) |
MDD unmedicated: 9 (29.03%) | MDD unmedicated: 6 (17.14%) | ||||
HAM-D17 mean (± SD) | n = 39 | n = 31 | n = 35 | n = 34 | H = 1.448, p = 0.485 |
12.13 ( ± 7.58) | 13.16 ( ± 8.75) | 14.26 ( ± 6.91) | 0.53 ( ± 0.96) | Across the MDD subgroups only (no controls) |
