Table 1 Cohort characteristics for ALSPAC and CHDS.

From: Prenatal cannabis exposure is associated with alterations in offspring DNA methylation at genes involved in neurodevelopment, across the life course

Cohort

Age (y)

N

Sample

Female (%)

PCE

PCTE

PTE

Tobacco smoking

Cannabis user

ALSPAC

Timepoint 1

0

858

Cord blood

448 (52.21%)

10 (1.51%)

30 (3.14%)

168 (19.58%)

  

Timepoint 2

7

924

Whole blood

473 (51.19%)

9 (1.08%)

22 (3.46%)

184 (19.91%)

  

Timepoint 3

15-17

922

Whole blood

484 (52.49%)

11 (1.19%)

21 (3.57%)

182 (19.73%)

  

CHDS

Timepoint 1

~27

98

Whole blood

27 (27.5%)

4 (4.08%)

13 (13.2%)

55 (56.1%)

28 (28.5%)

37 (37.5%)

  1. CHDS participants (27 y) were also classified for personal tobacco or cannabis usage as adults.
  2. PCE prenatal cannabis exposure controlled for prenatal tobacco exposure, PCTE prenatal cannabis exposure with tobacco co-exposure, PTE prenatal tobacco exposure only.
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