Fig. 3: Statistical and Genetic correlation between polygenic scores for autism and regional MRI-derived phenotypes. | Molecular Psychiatry

Fig. 3: Statistical and Genetic correlation between polygenic scores for autism and regional MRI-derived phenotypes.

From: Polygenic scores for autism are associated with reduced neurite density in adults and children from the general population

Fig. 3

A Cortical map of regional associations between PGS for autism and cortical MRI-derived phenotypes. Red outline means the effect of PGS for autism reached statistical significance at FDR <=0.05. B Cortical map of regional associations between PGS for autism and cortical MRI-derived phenotypes after global phenotype correction. Red outline means the effect of PGS for autism reached statistical significance at FDR <=0.05. For brevity, we have displayed only regional association maps for phenotypes where there was at least one significant regional association. C Genetic correlation between autism and regional ICVF in regions with statistically significant associations with the PGS for autism. Asterisks indicate p values after FDR correction: * p <= 0.05, ** p <= 0.01, *** p <= 0.001.

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