Fig. 5: White matter tract association.

Percentage of variance explained by polygenic score for autism (PGS) for 15 major white matter tracts for ICVF in UKB. Blue bar indicates negative associations, and the red bar indicates positive associations. * p <= 0.05. The acronyms for the 15 major white matter tracts are mcp = middle cerebellar peduncle, ml = medial lemniscus, cst = corticospinal tract, ar = acoustic radiation, atr = anterior thalamic radiation, str = superior thalamic radiation, pts = posterior thalamic radiation, slf = superior longitudinal fasciculus, ilf = inferior longitudinal fasciculus, ifo = inferior fronto-occipital fasciculus, unc = uncinate fasciculus, cgc = cingulate gyrus part of cingulum, cgh = parahippocampal part of cingulum, fmi = forceps minor, and fma = forceps major. Suffix _r means it is estimated from the right hemisphere and _l means it is estimated from the left hemisphere.