Fig. 6: Percentage of variance explained by sex-specific and sex-differentiating PGS for autism. | Molecular Psychiatry

Fig. 6: Percentage of variance explained by sex-specific and sex-differentiating PGS for autism.

From: Polygenic scores for autism are associated with reduced neurite density in adults and children from the general population

Fig. 6

A and B Percentage of variance explained by sex stratified autism PGS for the global phenotypes in the equivalent sexes in ABCD and UKB. C Percentage variance explained by the sex interaction analysis. Asterisks indicate P values after FDR correction: * P <= 0.05, ** P <= 0.01. mPGS = polygenic scores from the males-only GWAS, fPGS = polygenic scores from the females-only GWAS, and PGS:Sex = the interaction between sex and PGS. SA = surface area, CT = cortical thickness, MC = mean curvature, ICVF = intracellular volume fraction.

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