Fig. 4: Metabolic characterization of 4-month and 11-month-old 5xFAD mice. | Molecular Psychiatry

Fig. 4: Metabolic characterization of 4-month and 11-month-old 5xFAD mice.

From: Chronic social isolation-unpredictable stress induces early-onset cognitive deficits and exacerbates Aβ accumulation in the 5xFAD mouse model of Alzheimer’s disease

Fig. 4

A Left, body weight. Right, automated home-cage CLAMS monitoring system. B Accumulated food intake and total food intake during light and dark phase. C Accumulated water intake and total water intake during light and dark phase. D–H Real-time monitoring curve and the area under curve (AUC) quantification of D O2 consumption, E CO2 production, F respiratory exchange ratio (RER), G heat production, H horizontal activity, and I vertical activity in light and dark cycle. n = 5–8 male mice per group. *P < 0.05, **P < 0.01, ***P < 0.001, #P = 0.07 compared with WT mice.

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