Fig. 1: Schematic presentation of the study design.

The data was used to compared the four distinct trajectory groups (controls vs. pregnancy-only depression vs. postpartum-onset depression vs. persistent depression); to compare women with depression during pregnancy (pregnancy-only and persistent group) vs controls and then women depressed postpartum (postpartum-onset and persistent group) vs controls; as well as to assess the EPDS score as a continuous variable. APD Depression during pregnancy which could be persistent or resolved postpartum, PPD depression postpartum which could be persistent or postpartum-onset depression, STAR Spliced Transcripts Alignment to a Reference, DE Differential Expression.