Fig. 1: Comparisons of mean FC within and between the intrinsic brain networks showed significant group differences.

A Demonstration of the default mode network (33 ROIs); B All 36 large-scale network FC comparisons between ASD, FXS and TD groups. Squares with annotation of F value represent significantly altered large-scale network FC between the 3 groups (FDR corrected); C Significantly altered within- and between-network for the eight networks between ASD, FXS and TD groups; D Significant group differences in the mean FC of CN, DMN and between-network FC of DMN-CN, SMN-CN, VN-CN. VN visual network, SMN sensorimotor network, DMN default mode network, CN Cerebellum network. FDR-corrected p-value: *, p < 0.01; **, p < 0.001; ***, p < 0.0001. All statistical analyses were corrected for multiple comparisons using FDR (two-tailed).