Table 1 Baseline characteristics of participants, stratified by polygenic risk group.
Baseline characteristics | Overall (n = 12,029) | Low polygenic risk (Q1) (n = 2406) | Medium polygenic risk (Q2-4) (n = 7218) | High polygenic risk (Q5) (n = 2405) |
|---|---|---|---|---|
Age, mean (SD), years | 75.1 (4.2) | 75.3 (4.3) | 75.1 (4.3) | 74.8 (4.0) |
Sex, n (%) | ||||
Male | 5425 (45%) | 1040 (43%) | 3310 (46%) | 1075 (45%) |
Female | 6604 (55%) | 1366 (57%) | 3908 (54%) | 1330 (55%) |
Educational attainment, n (%) | ||||
< 9 years of education | 1840 (15%) | 333 (14%) | 1134 (16%) | 373 (16%) |
9–11 years of education | 3779 (31%) | 749 (31%) | 2245 (31%) | 785 (33%) |
12 years of education | 1343 (11%) | 274 (11%) | 798 (11%) | 271 (11%) |
13–15 years of education | 1898 (16%) | 418 (17%) | 1133 (16%) | 347 (14%) |
16 years of education | 1105 (9%) | 233 (10%) | 665 (9%) | 207 (9%) |
17–21 years of education | 2064 (17%) | 399 (17%) | 1243 (17%) | 422 (18%) |
Living status, n (%) | ||||
At home alone | 3812 (32%) | 753 (31%) | 2264 (31%) | 795 (33%) |
At home with family, friends, or a spouse | 8171 (68%) | 1644 (68%) | 4924 (68%) | 1603 (67%) |
In a residential homea | 46 (0.4%) | 9 (0.4%) | 30 (0.4%) | 7 (0.3%) |
BMIb, mean (SD), kg/m2 | 28.0 (4.5) | 27.6 (4.3) | 28.4 (4.8) | |
Smoking status, n (%) | ||||
Current | 367 (3%) | 59 (2%) | 217 (3%) | 91 (4%) |
Former | 4989 (41%) | 909 (38%) | 2997 (42%) | 1083 (45%) |
Never | 6673 (55%) | 1438 (60%) | 4004 (55%) | 1231 (51%) |
Alcohol drinking status, n (%) | ||||
Current | 9606 (80%) | 1985 (83%) | 5743 (80%) | 1878 (78%) |
Former | 584 (5%) | 76 (3%) | 364 (5%) | 144 (6%) |
Never | 1839 (15%) | 345 (14%) | 1111 (15%) | 383 (16%) |
