Fig. 3: Stronger evidence for reduced cortical tCho in datasets with better measurement quality.

Black circles represent the moving sample pooled effect size from 7 cortical datasets in ascending ranks of coefficients of variation (COVs) from poorer (left) to better COV (right) along the x-axis. Circle #1 is the effect size for seven datasets ranked 8–14. Circle #8 is for datasets ranked 1–7 (total k = 14). Mean COV for each set of 7 studies is given in parentheses along the x-axis. Red line is best-fitting logistic function. Inflection point is empirical threshold separating low- and high-quality datasets.