Table 1 Behavior.

Body weight [g] pre transponder surgery - 7 weeks

17.422 ± 0.28

16

16

t

Body weight [g] pre social boxes - 14 weeks

21.338 ± 0.31

16

16

t

IntelliCage - average total corner visits [#]

330.17 ± 17.112

12

9

U

IntelliCage - average total corner visits in dark phase [#]

261.18 ± 19.07

12

9

U

Elevated Plus Maze - total distance [m]

0.64 ± 0.04

16

16

t

Open Field Test - total distance [m]

3.70 ± 0.22

16

16

U

Latency to enter an open arm [s]

47.937 ± 8.86

16

16

U

Latency to enter an closed arm [s]

50.061 ± 7.88

16

16

U

Time in the open arms [s]

49.641 ± 6.94

16

16

U

Escape latency [s]

17.625 ± 2.4881

16

16

U

Time spent in peripheral zone [s]

336.32 ± 5.72

16

16

t

Time spent in intermediate zone [s]

54.466 ± 3.78

16

16

t

Time spent in center zone [s]

28.928 ± 2.83

16

16

t

Time in each zone

Two-way ANOVA

Trial 1 - Executive function [s/#]

0.64 ± 0.2785

16

16

t

Trial 2 - Executive function [s/#]

−0.40 ± 0.1786

16

16

U

Trial 1 vs. trial 2

Two-way Friedman

Habituation - Average escape latency open door [s]

9.53 ± 1.012

16

16

U

Challenge 1 - Average escape latency gateway [s]

9.38 ± 1.175

16

16

U

Challenge 2 - Average escape latency bedding [s]

78.349 ± 16.893

16

16

U

Challenge 3 - Average escape latency tissue plug [s]

42.50 ± 14.903

16

16

U

Challenge 4 - Average escape latency nesting material [s]

111.26 ± 22.278

16

16

U

Challenges

Two-way Friedman

Visible day 1 - escape latency [s]

9.84 ± 1.79

11

14

U

Visible day 2 - escape latency [s]

5.90 ± 2.3903

11

14

U

Visible day 1 -. Visible day 2

Two-way Friedman

Hidden day 1 - escape latency [s]

55.095 ± 6.96

11

14

t

Hidden day 2 - escape latency [s]

39.53 ± 6.34

11

14

U

Hidden day 3 - escape latency [s]

33.13 ± 6.73

11

14

U

Hidden day 4 - escape latency [s]

27.444 ± 5.33

11

14

t

Hidden day 5 - escape latency [s]

21.048 ± 4.86

11

14

U

Hidden day 6 - escape latency [s]

20.806 ± 3.16

11

14

U

Hidden day 7 - escape latency [s]

15.626 ± 2.83

11

14

U

Hidden day 8 - escape latency [s]

14.84 ± 1.63

11

14

t

Hidden day 1 - Hidden day 8

Two-way Friedman

Probe trial 1 - time in TQ [s]

34.281 ± 3.11

11

14

t

Reversal day 1 - escape latency [s]

42.663 ± 6.28

11

14

t

Reversal day 2 - escape latency [s]

32.892 ± 6.11

11

14

t

Reversal day 3 - escape latency [s]

12.18 ± 2.43

11

14

U

Reversal day 4 - escape latency [s]

12.134 ± 1.86

11

14

U

Reversal day 1 - Reversal day 4

Two-way Friedman

Probe trial 2 - time in TQ [s]

12.032 ± 1.671

11

14

t

Place Learning - cognition error

0.42 ± 0.03

14

12

t

Reversal Learning - cognition error

0.70 ± 0.03

14

12

t

Multiple Reversal Learning - cognition error

0.72 ± 0.03

14

12

U

Phase 1 Acquisition - cognition error

0.50 ± 0.05

12

11

t

Phase 1 Retrieval - cognition error

0.54 ± 0.06

12

10

U

Phase 2 Acquisition - cognition error

0.54 ± 0.04

12

9

t

Phase 2 Retrieval - cognition error

0.67 ± 0.04

12

9

t

Clockwise 1 - cognition error

0.29 ± 0.0101

12

9

t

Clockwise 2 - cognition error

0.25 ± 0.01

12

9

t

Counter-Clockwise 1 - cognition error

0.57 ± 0.01

12

9

t

Counter-Clockwise 2 - cognition error

0.55 ± 0.00

12

9

t