Fig. 3 | Mucosal Immunology

Fig. 3

From: Interleukin-22-deficiency and microbiota contribute to the exacerbation of Toxoplasma gondii-induced intestinal inflammation

Fig. 3

Small intestinal inflammation is independent of Reg3b expression. a–d B6 and Reg3b−/− mice were infected (I) or not (NI) by 35 cysts of T.gondii and intestinal samples were collected 7 days post infection (n = 4–5 mice per group). a IFNγ, IL-1β, IL-22, TIMP1, MPO, and LCN2 levels were determined by ELISA b Histological score of cell infiltration, exudate, edema and epithelium destruction was performed on 3 µm-thick paraffin embedded section after HE staining. c Representative HE staining of intestinal tissue. Scale bar: 200 µm. Values are expressed as mean ± SEM. *, **, and *** refer to P < 0.05, P < 0.01 and P < 0.001, respectively.

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