Table 1 Hierarchy of MAIT cell antigen potencies
From: Modulation of bacterial metabolism by the microenvironment controls MAIT cell stimulation
EC50 values (M) | ||||
---|---|---|---|---|
MAIT cells | TRBV | 5-OP-RU | 5-OE-RU | RL-6,7-diMe |
SMC3a | 20-1 | 5.329e−14 | 1.45e−10 | 4.603e−08 |
MRC25a | 6-1 | 8.757e−13 | 2.731e−09 | 2.332e−06 |
Donor 7b | Polyclonal | 3.083e−10 | 1.030e−08 | 2.618e−05 |
Donor 8b | Polyclonal | 3.027e−10 | 8.920e−09 | 3.267e−05 |
Donor 9b | Polyclonal | 1.888e−11 | 7.558e−10 | 1.970e−05 |
Donor 10b | Polyclonal | 2.949e−10 | 2.501e−09 | 1.887e−05 |
Donor 11b | Polyclonal | 1.864e−10 | nd | 8.189e−06 |