Fig. 3
From: Epigallocatechin-3-gallate local pre-exposure application prevents SHIV rectal infection of macaques
SHIV RNA and DNA detection in multiple tissues necropsied at week 36 post first SHIV challenge. SHIV RNA (a) and DNA (b) assays in the indicated tissues from the animals of PBS control (red symbols, n = 6–8) and EGCG group (green symbols, n = 8) at necropsy. Log10 SHIV copies 2 μg−1 total genomic RNA or DNA equivalents are shown. Symbols represent individual animals and are pooled from three independent experiments. Triplication tissue samples were conducted in each independent experiment. The dot line: the detection threshold. GI gastrointestinal tract, LN lymph nodes, Jej-Mes jejunal mesenteric, Col-Mes colonal mesenteric, IEL intraepithelial lymphocytes
