Fig. 5
From: MAdCAM costimulation through Integrin-α4β7 promotes HIV replication
Naive CD4+ T cells stimulated with RA and MAdCAM support viral replication. Replication of HIV SF162 in purified CD45RO−/CD4+ T cells from four independent donors, where cells were stimulated with anti-CD3 alone or in combination with MAdCAM, RA, or anti-CD28 as designated, for 3 days prior to infection. Viral replication was quantified by p24 AlphaLISA (y-axis) on days 4 (purple) and 7 (red) post-infection (x-axis). The purity of CD45RO−/CD4+ T cell cultures assessed on day 0, is shown
