Fig. 6
From: MAdCAM costimulation through Integrin-α4β7 promotes HIV replication
MAdCAM stimulation of PBMCs from HIV-infected subjects promotes viral replication. PBMCs isolated from six HIV-infected donors were CD8+ T cell depleted, and cultured over ligand-coated plates. The stimulatory ligands include anti-CD3, anti-CD28, MAdCAM and RA in various combinations as designated. Viral p24 was measured by AlphaLISA (y-axis) from culture supernatants at day 7, 11, 14, and 18 (x-axis)
