Fig. 7
From: C3a receptor antagonism as a novel therapeutic target for chronic rhinosinusitis
Quantification of sinonasal inflammation, epithelial injury, and goblet cell hyperplasia demonstrates the protective effect of complement C3a receptor deficiency and therapeutic antagonism. a Inflammatory cell infiltrate, b eosinophil accumulation, c goblet cell hyperplasia, and d epithelial injury/thickness. Data are expressed as mean ± SE. All statistical analysis are pairwise comparisons, control wild-type vs. wild-type Af (#p < 0.001), wild-type Af vs. C3aR−/− Af (##p < 0.01), wild-type Af vs. C3aR i.n. (*p < 0.01), wild-type Af vs. C3aR i.p. (**p < 0.01)
