Fig. 3

Eicosanoid mediators but not their receptors are increased in lung in severe eosinophilic asthma in the Oxford cohort. a Expressions of CRTH2 (upper panel) and CysLT1 (bottom panel) in individual Tc2 cells were paired compared between healthy controls and severe asthma groups with flow cytometry. b Levels of PGD2 (upper panel) and LTE4 (bottom panel) in sputum determined with ELISA were compared between healthy controls and severe asthma groups. *p < 0.05