Fig. 3
Colonization with EC-ovaOM and EC-ovaSECR induces tolerance in an OVA-induced allergic lung inflammation model. a Experimental setup. b Eosinophil, CD4+ and CD8+ T cell numbers in BAL analyzed by FACS. For gating strategy see Supplementary Figure 6. Data are expressed as mean fold change ± SEM compared to ECCTRL. c mRNA expression in lung tissue for Il4 and Il13 expressed as log2 fold change (FC) compared to log mean of the ECCTRL condition. Boxes and whiskers indicate median, and 10/25/75/90 percentiles. b/c Data of 4 experiments with 4 mice per group, respectively, are shown (total n = 16 per group). Statistical differences were determined by one-way ANOVA following Dunn’s post hoc test (test did not include Neg Ctrl). *p < 0.05; **p < 0.01; ***p < 0.001. d Representative H&E stained lung sections
