Fig. 4
From: Low nadir CD4+ T-cell counts predict gut dysbiosis in HIV-1 infection
Fecal short-chain fatty acid (SCFA) levels. a Fecal butyric and propionic acid levels were significantly higher in subjects with low-gene counts (LGC), whereas isovaleric acid levels were higher in subjects with high gene counts (HGC); no significant differences in SCFAs were observed between different nadir CD4+ T-cell count categories. b The acetyc/butyric ratio was significantly higher in HGCs than in LGCs, but was not significantly different by nadir CD4+ T-cell counts. c Butyrate levels were positively correlated with abundance of Roseburia intestinalis and Roseburia inulinivorans, two well-known butyrate producers. Only statistically significant correlations are shown (p < 0.05). d Abundance of R. intestinalis and R. inulinivorans across microbial gene richness values (HGC in green, LGC in orange). *(p < 0.05)
