Fig. 3 | Mucosal Immunology

Fig. 3

From: E. coli Nissle 1917 is a safe mucosal delivery vector for a birch-grass pollen chimera to prevent allergic poly-sensitization

Fig. 3

Intranasal pretreatment with EcN-Chim reduces allergen-specific IgE in serum and induces high levels of IgA in BAL. Mice were treated as indicated in Fig. 2a. Serum samples were obtained from mice blood collected on day 51. Allergen-specific antibody levels in mouse sera or in bronchial lavages (BAL) were determined by ELISA. a Levels of Bet v 1, Phl p 1, Phl p 5-specific serum IgE and b allergen-specific IgA levels in BAL. a, b represents mean ± SEM from pooled data of two independent experiments (total n = 10 mice per group). Error bars show mean ± SEM. *P < 0.05, **P < 0.01 by Mann−Whitney U- test

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