Fig. 5
CD8 TVM cells are sufficient to confer innate non-cognate protection against bacterial infection. B6 WT mice were infected with Hp and naïve (CD44lo) or CD8 TVM (CD44hiCD49dlo) cells were sorted from the pooled mesLN and spleen 2 weeks later. A total of 2 × 106 cells were transferred into naïve IFNγ KO recipients, which were infected with 2 × 105 Lm the next day. Bacterial burden in liver and spleen was determined at day 3. Data were pooled from two independent experiments. Solid bar depicts mean. X indicates individual mice that had succumbed to infection prior to analysis. ns, not significant; *P < 0.05; **P < 0.01; ****P < 0.0001 by one-way ANOVA
