Fig. 8 | Mucosal Immunology

Fig. 8

From: GITRL on inflammatory antigen presenting cells in the lung parenchyma provides signal 4 for T-cell accumulation and tissue-resident memory T-cell formation

Fig. 8

GITRL expression is mediated in part by IFN-I during influenza infection. a, b Mice were injected i.p. with IFNAR blocking or isotype control antibodies at day −1 and 0 prior to influenza A/PR8 infection. Gating strategy is shown in a and GITRL expression on InfAPC and cDC in the lung at day 3 p.i. summarized in b, with representative staining shown below. dMFI refers to the MFI for the specific antibody stain minus the FMO control. Data from b pooled from two independent experiments with a total of six mice per group. InfAPC inflammatory APCs

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