Fig. 2 | Mucosal Immunology

Fig. 2

From: Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis

Fig. 2

Enhanced ileal innate and adaptive Th1 immune responses in pediatric iCD ≥10 years at diagnosis. a Top functional annotation enrichment analyses using Toppgene/ToppCluster25 platforms of the 171 upregulated and differentially expressed genes between older and younger iCD and Cytoscape26 was used for visualization. b Top functional annotation enrichment analyses using Toppgene/ToppCluster25 platforms using the 194 downregulated and differentially expressed genes between older and younger iCD and Cytoscape26 was used for visualization

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