Table 2 Clinical and demographic characteristics

From: Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis

 

Ctl n = 50

cCD n = 56

iCD n = 198

iCD A1a n = 48

iCD A1b n = 150

Mean (SD) age (years)

11.8 (3)

12.4 (3)

12.2 (3)

8.6 (1)

13.4 (2)

Male gender (%)

62

59

63

67

59

Location L1 (%)

-

-

28

15*

33

Perianal involvement (%)

-

21

16

10

17

Ileal deep ulcers (%)

-

-

45

45

46

PCDAI at diagnosis (n)

 

n = 52

n = 197

n = 47

n =  150

< = 10 (inactive, %)

-

6

9

11

8

11 to 30 (mild, %)

-

48

52

46

53

>30 (moderate-severe, %)

-

46

39

42

39

  1. PCDAI Pediatric Crohn Disease Activity Index at diagnosis prior to treatment, L1 ileal location
  2. Younger vs older *p  =  0.015
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