Fig. 3
From: A role for BATF3 in TH9 differentiation and T-cell-driven mucosal pathologies
TL1A enhances binding of BATF, IRF4, and BATF3 to the Il9 promoter during TH9 differentiation. a, b Naive murine CD4+ T cells were differentiated under TH0- or TH9-polarizing conditions with or without TL1A for 2 (BATF, IRF4, and AcH3), or 3 (BATF3) days. ChIP assays were performed for BATF, IRF4, BATF3, or AcH3 binding to conserved noncoding sequences (CNS) 1 (a) and CNS0 (b) of Il9. Data represent means ± SD of one independent experiment out of two independent experiments. *p < 0.05, **p < 0.01, ***p < 0.005 as determined by Student’s t test
