Fig. 1
From: JunB plays a crucial role in development of regulatory T cells by promoting IL-2 signaling
JunB is required for the development of T cell-mediated autoimmune disease models. a Control (Junbfl/fl) or Junbfl/flCd4-Cre mice were immunized with MOG31-55 peptide, and the clinical scores were measured. Results are means ± SEMs (n = 6–7 mice per each genotype). b Control or Junbfl/flCd4-Cre mice were intraperitoneally injected with anti-CD3 antibody (20 μg per mouse) at day 0, 2, and 4. Body weight was measured every 24 h. The average of body weight is shown as percentage relative to the initial value. Results are means ± SEMs (n = 7 mice per each genotype). *p < 0.05, **p < 0.01, and ***p < 0.001 (two-tailed Student’s unpaired t test)
