Fig. 3
From: JunB plays a crucial role in development of regulatory T cells by promoting IL-2 signaling
The number of IFN-γ-producing pathogenic T cells is not increased in the colon of Junbfl/flCd4-Cre mice after DSS administration. a Colonic lamina propria cells were isolated from untreated mice or mice administrated with DSS for 5 days, and analyzed by flow cytometry. Representative results of flow cytometry are shown (n = 4 mice). As shown in Supplementary Figure 2, FVD506−CD45.2+CD4+TCRβ+ cells (CD4+ T cells) are presented. b, c Average percentages of IFN-γ+ cells (b) or IL-17A+ cells (c) among CD4+ T cells are shown. Results are means ± SEMs (n = 4–6 mice per each genotype). *p < 0.05, **p < 0.01, ****p < 0.0001, n.s. not significant (two-tailed Student’s unpaired t test)
