Fig. 4 | Mucosal Immunology

Fig. 4

From: Spliceosome protein Eftud2 promotes colitis-associated tumorigenesis by modulating inflammatory response of macrophage

Fig. 4

Myeloid Eftud2 knockout has no impact on macrophage and neutrophil chemotaxis in CAC lesions. a On day 35 and 100 after CAC induction, the colons of MKO and WT mice were dissected and Macrophage (F4/80+) and neutrophil (Gr-1+) infiltrates in the colons were detected by immunohistochemistry. Six pairs of mice were analyzed. Left: typical results; Magnification: ×200. Right: summarized results; HPF, high-power field. b, c On day 35 and 100 after CAC induction, the colons of MKO and WT mice were dissected and the levels of chemokines indicated in the colons were determined by ELISA (b) and quantitative RT-PCR (c). The data were pooled from two independent experiments. Each group consists of 6–8 mice

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