Fig. 2
From: A pro-inflammatory CD8+ T-cell subset patrols the cervicovaginal tract
T-cells in the endocervix, ectocervix and vaginal tissue display similar phenotypes and transcription patterns. a Mean frequencies (±SD) of CD4+ and CD8+ T-cells expressed as percentages of CD3+CD45+ live cells in endocervical (EndoCx), ectocervical (EctoCx) and vaginal tissue (VT) were determined by flow cytometric staining. b Mean frequencies (±SD) of naïve (CCR7+ CD45RA+), activated (CD127dim CD25+), effector memory (Tem, CCR7−) and central memory (Tcm, CCR7+ CD45RA−) CD8+ T-cells in the 3 CVT tissues. c Mean frequencies (±SD) of CCR5, CXCR3, CD49a, and PD-1 as percentages of DN (top), CD69+ (middle) and CD69+CD103+DP (bottom) T-cells for EndoCx, EctoCx and VT. n = 5. To test for statistical significance, a Kruskal–Wallis test was performed with Dunn’s multiple comparisons test. d Heatmap showing the RNA expression patterns of DP, SP, and DN CD8+ T-cells within the blood and the three types of CVT tissues
