Fig. 6
From: A pro-inflammatory CD8+ T-cell subset patrols the cervicovaginal tract
The frequency of DN Tim cells increases in the CVT of HIV-infected women while the transcriptional pattern remains stable. a Mean frequencies (±SD) of DN, SP, and DP cells in the CVT of women grouped based on their HIV, BV, and HSV status. b Mean levels (±SD) of IL-1a and IL-15 were measured from cervicovaginal fluids by MSD assay. Statistical significance was determined by unpaired t-test or Mann–Whitney test. c Principal component analysis and d volcano plot obtained from the transcriptional data of the three populations of CD8+ T-cells (DN, SP, and DP) from HIV-positive and HIV-negative women
