Table 1 Patient characteristics

From: IL-10 signaling in dendritic cells controls IL-1β-mediated IFNγ secretion by human CD4+ T cells: relevance to inflammatory bowel disease

 

I

II

III

Number

3

38

20

Age in years, range

13–15

8–18

8–17

Male (n)

1

19

10

Female (n)

2

19

10

Diagnosis

 Ulcerative colitis

 

16

9

 Crohn’s disease

3

20

11

 IBD unclassified

 

2

 

 Age at diagnosis (years)

7–11

8–18

5–16

Treatment at time of analysis

 No

 

38

3

 Azathioprine

2

 

7

 Mesalazine

  

2

 Infliximab

  

6

 Methotrexate

1

 

1

 Prednisolone

  

4

 Adalimumab

1

 

3

 6-Mercaptopurine

  

1

Treatment history

 Azathioprine

3

  

 Mesalazine

2

  

 Infliximab

3

  

 Methotrexate

1

  

 Prednisolone

3

  

 Adalimumab

3

  

6-Mercaptopurine

 Surgery

3

 

10

  1. Cohort I, related to Fig. 2g–i and Supplementary Figure 2; Cohort II, related to Fig. 4b, f; Cohort III, related to Fig. 4a, d, e