Fig. 2
From: TOLLIP deficiency is associated with increased resistance to Legionella pneumophila pneumonia
Cytokine responses from WT and Tollip−/− mice after L. pneumophila (Lp) aerosol infection. Mice were infected with 106 CFU WT Lp Philadelphia-1 strain and after 24 h, cytokine concentrations were measured from bronchoalveolar (BAL) fluid and serum. a BAL cytokine concentrations measured by ELISA from WT and Tollip−/− mice. *p < 0.05, Student’s two-sided t test. b BAL cytokines, measured by Luminex cytokine assay 24 h after Lp aerosol infection. *p < 0.05, **p < 0.01, ***p < 0.001, at 1% false discovery rate. Error bars represent±SEM. c Serum cytokine concentrations measured by ELISA. *p < 0.05, Student’s two-sided t test. Error bars represent±SEM. Data are representative of three independent experiments with N = 5 in each group
