Fig. 5
From: Lypd8 inhibits attachment of pathogenic bacteria to colonic epithelia
Lypd8 binding to intimin-deficient C. rodentium was substantially reduced. a In the course of antibiotic (vancomycin and chloramphenicol) treatment, WT and Lypd8−/− mice were orally infected with WT or lafA, escN, or eae-deficient strains expressing GFP. Lypd8 binding to each C. rodentium strain in fecal samples was analyzed by flow cytometry using anti-Lypd8 antibody. b Lypd8 binding to each GFP-expressing bacterial strain in fecal bacteria is shown using histogram charts. c Bars indicate the percentage of Lypd8 binding to each strain (n = 3 per group). Data are shown as mean ± SD. One-way ANOVA was used to determine a significant difference between groups. *p < 0.05, n.s: not significant. d Lypd8 binding to the eae/lafA double-mutant strain is shown using histogram charts
